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X-WR-CALNAME:EPIC Emerging & Pandemic Infections Consortium
X-ORIGINAL-URL:https://epic.utoronto.ca
X-WR-CALDESC:Events for EPIC Emerging & Pandemic Infections Consortium
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SUMMARY:Annual Meeting of the American Society of Tropical Medicine & Hygiene
DESCRIPTION:The American Society of Tropical Medicine & Hygiene Annual Meeting is the premier international forum for the exchange of scientific and clinical advances in tropical medicine\, hygiene and global health. World-class research findings\, clinical updates and topical discussions about the hot-button global issues from the world’s brightest scientific experts and thought leaders are presented over five days. \nThe scientific program is designed for researchers\, professors\, government and public health officials\, military personnel\, travel clinic physicians\, practicing physicians in tropical medicine\, students\, and all healthcare providers working in the fields of tropical medicine\, hygiene\, and global health. The meeting draws thousands of tropical medicine and global health professionals representing academia\, foundations\, government\, not-for-profit organizations\, non-governmental organizations\, the private sector\, the military\, and private practice. \nJoin us for plenary sessions\, science and clinical sessions and an exhibit hall featuring the latest products and services. \nRegister for the ASTMH annual meeting here! \nWhen: November 9-13\, 2025 \nWhere: Metro Toronto Convention Centre\, Toronto\, ON
URL:https://epic.utoronto.ca/event/annual-meeting-of-the-american-society-of-tropical-medicine-hygiene/
LOCATION:Metro Toront Convention Centre\, 255 Front Street W\, Toronto\, Ontario\, M5V 2W6\, Canada
CATEGORIES:Conference,Hybrid
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DTSTART;TZID=America/Toronto:20251110T150000
DTEND;TZID=America/Toronto:20251110T160000
DTSTAMP:20260419T233232
CREATED:20251104T212620Z
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UID:6802-1762786800-1762790400@epic.utoronto.ca
SUMMARY:Systematic Genetic Analysis of the Epstein-Barr Virus B-cell Lytic Switch
DESCRIPTION:Join the Department of Molecular Genetics for a seminar with Ben Gewurz\, who is a Professor of infectious Diseases at Harvard University. \nGewurz will present a talk titled “Systemic genetic analysis of the Epstein-Barr virus B-cell lytic switch”\, hosted by Lori Frappier. Read below for more details. \nWhen: November 10th\, 3:00 – 4:00 p.m. \nWhere: Rm 2170\, Medical Sciences Building\, University of Toronto \nEpstein-Barr virus (EBV) uses a biphasic lifecycle\, switching between latent and lytic phases to persistently infect most adults. Latency enables EBV to evade immune responses to over 70 viral lytic proteins and used by most of the 200\,000 EBV-associated cancers/year. EBV reactviation is increasingly implicated in autoimmune diseases\, including multiple sclerosis\, and in tumor microenvironment. However\, mechanisms that regulate EBV reactivation have remained incompletely understood. Gequrz used CRISPR-Cas9 human genome-wide screens to define host factors that control the viral B-cell lytic switch. These highlighted MYC and the LSD1/CoREST/ZNF217 complex as key repressors of the lytic switch\, who control expression of a pro-lytic viral lncRNA\, which in turn controls higher order viral genome structure through long-range DNA interactions.
URL:https://epic.utoronto.ca/event/systematic-genetic-analysis-of-the-epstein-barr-virus-b-cell-lytic-switch/
LOCATION:MSB 2170\, 1 King's College Circle\, Toronto\, ON\, M5S 1A8\, Canada
CATEGORIES:Seminar
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