Darrell Tan (Photo: Kevin Van Paassen) 19 December 2025 By Christine Davidson This article was originally published on the Unity Health Toronto News website. Darrell Tan, infectious diseases physician at St. Michael’s Hospital and member of the Emerging & Pandemic...
SickKids-led study reveals promising gut-targeted therapy for C. difficile infections
Using the structure of C. diff's toxin B and its interactions with bile acids as a blueprint, the research team designed new synthetic bile acids that stay in the gut longer. This gut-restricted design helps the compounds work right where the toxin causes harm,...
Study reveals how the gut builds long-lasting immunity after viral infections
Professor Jen Gommerman (left) and postdoctoral fellow Kei Haniuda 18 November 2025 By Betty Zou A new study led by University of Toronto researchers has shown that immune cells in the gut follow an atypical pathway to produce antibodies that provide long-term...
Mpox online image atlas launches to help reduce stigma, improve representation and enhance access to care
From left: Darrell Tan, Sharon Sukhdeo, and Garfield Durrant 11 November 2025 By Betty Zou A team of clinicians at Unity Health Toronto and the University of Toronto has created a new resource to help health care providers detect mpox earlier and to help patients get...
Study discovers Salmonella cell-to-cell transmission is regulated by a cellular protein linked to early onset Parkinson’s disease
Anna Waldmann and John Brumell 10 November 2025 By Aideen Teeling Researchers at The Hospital for Sick Children (SickKids) have discovered that a host protein linked to early onset Parkinson’s disease promotes the spread of Salmonella bacteria between cells. Upon...
Mango Device Offers Sweet Solution to Biomanufacturing Challenges
PhD trainee Pouriya Bayat prepares Mango for diagnostic test. October 28, 2025 By Eileen Hoftyzer This story was originally published on the Leslie Dan Faculty of Pharmacy's website. The portable device, developed by the Pardee lab, allows decentralized diagnostics...
Scientists identify first virus to infect Legionella, revealing evolutionary origins of Legionnaire’s disease
From left: Elizabeth Chaney, Alexander Ensminger, Beth Nicholson and José Santé September 23, 2025 By Betty Zou University of Toronto researchers have made the first discovery of a virus that infects Legionella pneumophila, the bacteria that causes Legionnaires’...
Study reveals how bacterial signal triggers intestinal stem cell regeneration
Shawn Goyal (left) and professor Stephen Girardin September 15, 2025 By Betty Zou A University of Toronto team of researchers has found that bacteria can drive stem cell regeneration to repair the intestinal lining after injury. The study, published in Cell Stem...
Viruses preserve their progeny through newly discovered anti-Kronos effect: study
Research associate Véronique Taylor (left) and professor Karen Maxwell August 12, 2025 By Betty Zou In a new study published in Nature, University of Toronto researchers have discovered how bacterial viruses protect their offspring to maximize...
A new bivalent vaccine offers hope for preventing antibiotic-resistant Neisseria gonorrhoeae infections
(left to right) Jamie Fegan and Epshita Islam with Trevor Moraes By Sunitha Chari Researchers at the University of Toronto have developed a new vaccine formulation for the sexually transmitted infection (STI) gonorrhea. The formulation comprises two antigens derived...
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